May 22, 2008

HIV Vaccine

Here's an article about the failure of HIV vaccines.

I think the most interesting bit is this:

"While scientists hoped the Merck vaccine might prevent some infections, its chief purpose was to stimulate "cell-mediated" immunity to produce a less severe illness. Specifically, the vaccine was expected to lower the "viral load" of HIV in the bloodstream, which in turn would both prolong survival and lessen the chance the person would infect others."

Vaccines work by teaching your immune system to recognize viruses and produce anti-bodies to prevent them from replicating excessively.  Vaccines don't actually keep you from getting the disease.  Some of the 24 hour bugs you've had may have been bugs you've caught many times before.  The symptoms don't last long because your body recognizes the virus and quickly starts producing the right anti-bodies to get rid of them.

That's why an HIV vaccine isn't likely to be successful.  People will still be infected with HIV, their immune systems compromised by default.  And the danger remains that HIV replicates poorly and thus, mutates easily.  I think the traditional vaccine makes a poor avenue of research into HIV.

Posted by: roggowj at 06:16 PM | No Comments | Add Comment
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